Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Researchers at the University of Bristol have caught DNA-copying enzymes generating long stretches of genetic code without any template to guide them, a behavior the team calls “doodling.” Published ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Scientists used a bacterial system called retron to turn DNA into a programmable tool inside living cells, enabling gene ...

Patients with this genetic disorder have a form of dwarfism — they are short in stature and have underdeveloped ears and ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

Most of the cells in our body carry the genome, and those cells are constantly bombarded with environmental influences including UV rays, pollution, alcohol, and other exposures that can damage the ...

Tampa (BLOOM) – Understanding the intricate process of aging has been a subject of fascination for scientists and researchers. While aging is a natural part of life, recent studies have shed light on ...