The establishment and maintenance of neuronal identity are critically dependent on a finely tuned interplay between transcription factors and the epigenetic landscape. Central to this network is the ...

In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...

Their findings, recently reported in the journal Nature, overturn longstanding assumptions in developmental biology and could ...

A study by IRB Barcelona unveils how the lack of a fraction of the CPEB4 protein causes a decrease in the expression of genes that are crucial for neuronal development. Published in the journal Nature ...

How does the neural tube close? A new study uses physics-based modeling to reveal the actin "purse-string" mechanism and cellular coordination that prevents spina bifida.

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

When do peripheral nerves develop? Researchers used "mosaic barcodes" to prove that neural crest cells commit to their ...

In the brain, highly specific connections called synapses link nerve cells and transmit electrical signals in a targeted manner. Despite decades of research, how synapses form during brain development ...

A new study unveils how the lack of a fraction of the CPEB4 protein causes a decrease in the expression of genes that are crucial for neuronal development. A study by IRB Barcelona unveils how the ...