In general, the most common type of immunodeficiencies are called antibody deficiencies. Roughly about two-thirds of all primary immunodeficiency diseases involve antibody deficiencies or combined ...

Given the heterogeneity and rarity of inborn errors of immunity (IEIs), management guidelines that deal with primary immunodeficiency as a whole are rare. The most recent general guideline, the ...

Primary immunodeficiency (PI) is a group of more than 400 disorders that affect the immune system. In people with PI, the immune system is weakened or missing important components, making it harder ...

A single treatment with a CRISPR-Cas9 based gene editing therapy is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful ...

Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing the first line of defense against ...

Primary immunodeficiency (PI) not only increases your risk of frequent and serious infections, but can also make you more likely to develop autoimmune diseases — conditions where the immune system ...